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Cuelure is primarily used in integrated pest management strategies to control fruit fly populations. It is particularly effective against pests like the melon fly (Bactrocera cucurbitae) and Queensland fruit fly (Bactrocera tryoni). When deployed in traps or kill zones, it attracts male fruit flies, interrupting their ability to reproduce and reducing infestation rates.

This compound is especially significant in tropical regions like Indonesia, where fruit flies pose a major threat to crops such as melons, papayas, and guavas. By minimizing the need for broad-spectrum insecticides, Cuelure helps maintain ecological balance while protecting agricultural yields.

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