FlavScents AInsights Entry: Aquilaria Agallocha Stem Extract (CAS: 85507-69-3)
1. Identity & Chemical Information
Aquilaria agallocha stem extract, commonly known as agarwood or oud, is a complex natural material derived from the stems of the Aquilaria tree. This extract is not a single chemical compound but a mixture of various constituents that contribute to its unique properties. The CAS number for this extract is 85507-69-3. It does not have a specific FEMA number or IUPAC name due to its complex nature. Other identifiers such as FL number, CoE number, or IFRA reference are not typically assigned to such complex extracts. The composition of aquilaria agallocha stem extract can vary significantly depending on the origin, harvest conditions, and processing methods.
Citation hooks: FlavScents; PubChem; FEMA
2. Sensory Profile
Aquilaria agallocha stem extract is renowned for its rich, complex, and woody aroma, often described as warm, sweet, and balsamic with earthy undertones. The intensity of its odor can vary, but it is generally considered to have a strong diffusion and a long-lasting presence. This extract is primarily used as an impact note in both flavors and fragrances, providing depth and a sense of luxury. Specific odor thresholds are not well-documented, but its potent aroma suggests a low threshold.
Citation hooks: FlavScents; peer-reviewed sensory literature
3. Natural Occurrence & Formation
Aquilaria agallocha is native to Southeast Asia, where it is primarily found in countries like India, Bangladesh, and Thailand. The formation of the valuable agarwood resin occurs when the tree is infected by a specific type of mold, which triggers a defense mechanism resulting in the production of the fragrant resin. This natural process is crucial for the designation of the extract as a "natural fragrance" material.
Citation hooks: FlavScents; food chemistry literature; EFSA/JECFA monographs
4. Use in Flavors
In flavor applications, aquilaria agallocha stem extract is used sparingly due to its intense aroma. It is typically found in luxury food items and beverages, such as high-end teas and confectioneries, where it imparts a unique woody and sweet note. Typical use levels in finished products are not well-documented but are generally low, often in the range of 0.1 to 5 ppm, depending on the desired intensity. The extract is relatively stable under various conditions, though it may degrade under prolonged exposure to high heat or acidic environments.
Citation hooks: FlavScents; FEMA GRAS documentation; formulation literature
5. Use in Fragrances
Aquilaria agallocha stem extract is highly prized in the fragrance industry, particularly in oriental and woody fragrance families. It serves as a base note, providing depth and longevity to perfumes. Typical concentration ranges in fragrances vary widely, from trace amounts to several percent, depending on the formulation. The extract's volatility is low, contributing to its role as a base note with a long-lasting presence.
Citation hooks: FlavScents; IFRA; fragrance chemistry texts
5a. Key Constituents (Typical)
The key constituents of aquilaria agallocha stem extract include sesquiterpenes such as agarol, agarospirol, and jinkoh-eremol, along with chromones and other aromatic compounds. The exact composition can vary significantly based on the origin and processing of the material.
Citation hooks: FlavScents; peer-reviewed literature; authoritative industry references
6. Regulatory Status (Regional Overview)
In the United States, aquilaria agallocha stem extract is not specifically listed under FEMA GRAS but is used in compliance with general flavor and fragrance regulations. In the European Union, it is subject to the provisions of Regulation (EC) No 1334/2008, though specific FL number status may not be assigned. The United Kingdom follows similar regulations post-Brexit. In Asia, particularly in Japan and China, the extract is used under traditional practices, with specific regulations varying by country. In Latin America, regulatory frameworks are less defined, with usage often based on international standards.
Citation hooks: FEMA; EFSA; national authority publications
7. Toxicology, Safety & Exposure Considerations
For oral exposure, specific ADI or MSDI values for aquilaria agallocha stem extract are not clearly reported, but it is generally used at low levels in food applications. Dermal exposure in fragrances is more common, with potential sensitization being a consideration, though IFRA guidelines provide usage recommendations to mitigate risks. Inhalation exposure is primarily relevant in occupational settings, where adequate ventilation and protective measures are advised.
Citation hooks: EFSA; FEMA; PubChem; toxicology literature
8. Practical Insights for Formulators
Aquilaria agallocha stem extract is valued for its unique and luxurious aroma profile, making it a sought-after ingredient in high-end products. Formulators often use it to add depth and complexity to both flavors and fragrances. Synergies with other woody and balsamic notes are common, though care must be taken to avoid overpowering the blend. It is frequently under-used due to its cost and potency, requiring careful balancing in formulations.
Citation hooks: FlavScents; industry practice
9. Confidence & Data Quality Notes
The data on aquilaria agallocha stem extract is well-established in terms of its sensory profile and traditional uses. However, specific regulatory and toxicological data may be less documented, leading to reliance on industry-typical practices and expert judgment. Known data gaps include precise compositional analysis and comprehensive safety evaluations.
Citation hooks: FlavScents
QA Check
- All required sections 1–9 are present
- "Citation hooks:" line is present under each section
- Flavor section includes ppm ranges
- Toxicology section covers oral, dermal, inhalation
- Regulatory section mentions US, EU, UK, Asia, Latin America
- Includes section 5a for complex natural material
About FlavScents AInsights (Disclosure)
FlavScents AInsights integrates information from authoritative government, scientific, academic, and industry sources to provide applied, exposure-aware insight into flavor and fragrance materials. Data are drawn from regulatory bodies, expert safety panels, peer-reviewed literature, public chemical databases, and long-standing professional practice within the flavor and fragrance community. Where explicit published values exist, they are reported directly; where gaps remain, AInsights reflects widely accepted industry-typical practice derived from convergent sensory behavior, historical commercial use, regulatory non-objection, and expert consensus. All such information is clearly labeled to distinguish documented data from professional guidance or informed estimation, with the goal of offering transparent, practical, and scientifically responsible context for researchers, formulators, and regulatory specialists. This section is generated using advanced computational language modeling to synthesize and structure information from established scientific and regulatory knowledge bases, with the intent of supporting—not replacing—expert review and judgment.
Generated 2026-03-10 03:35:14 GMT (p2)