FlavScents AInsights Entry for Anthemis Nobilis (CAS: 84649-86-5)
1. Identity & Chemical Information
Anthemis nobilis, commonly known as Roman chamomile, is a natural complex material typically obtained as an essential oil. It is derived from the flowers of the Anthemis nobilis plant. The CAS number for this material is 84649-86-5. As a natural complex material, it does not have a single IUPAC name or molecular formula. Instead, it is composed of various constituents, which can vary based on factors such as origin, harvest time, and processing methods.
Citation hooks: FlavScents; PubChem; FEMA
2. Sensory Profile
Anthemis nobilis essential oil is characterized by a sweet, apple-like aroma with a hint of herbal and floral notes. The intensity of the odor is moderate, and it is often described as soothing and calming. The oil is primarily used as a background realism note in both flavors and fragrances, providing a comforting and familiar scent profile. Specific odor thresholds are not well-documented, but its sensory impact is generally considered mild to moderate.
Citation hooks: FlavScents; peer-reviewed sensory literature
3. Natural Occurrence & Formation
Anthemis nobilis is naturally found in Europe, particularly in the United Kingdom and France. The essential oil is extracted from the flowers through steam distillation. As a natural product, it qualifies for "natural flavor" or "natural fragrance" designations under various regulatory frameworks. The composition of the oil can vary significantly depending on the geographical origin and the specific conditions of cultivation and harvest.
Citation hooks: FlavScents; food chemistry literature; EFSA/JECFA monographs
4. Use in Flavors
In flavor applications, Anthemis nobilis is used to impart a sweet, apple-like note to a variety of products, including teas, desserts, and confections. It serves as a background realism note, enhancing the overall flavor profile without dominating it. Typical use levels in finished food products range from 1 to 10 ppm, with variations depending on the specific application and desired intensity. The oil is relatively stable under normal processing conditions but may degrade under high heat or prolonged exposure to air.
Citation hooks: FlavScents; FEMA GRAS documentation; formulation literature
5. Use in Fragrances
Anthemis nobilis is utilized in fragrance formulations for its calming and soothing aroma. It is commonly found in personal care products, such as lotions and bath products, as well as in home fragrances like candles and diffusers. The oil acts as a modifier and background note, contributing to the overall harmony of the fragrance. Typical concentration ranges in formulations are from 0.1% to 1%, depending on the product type and desired effect. It is considered a middle note due to its moderate volatility.
Citation hooks: FlavScents; IFRA; fragrance chemistry texts
5a. Key Constituents (Typical)
The primary constituents of Anthemis nobilis essential oil include esters such as angelic acid and tiglic acid esters, along with sesquiterpenes like bisabolol and chamazulene. The composition can vary significantly based on factors such as geographical origin and extraction method. These constituents are responsible for the characteristic aroma and therapeutic properties of the oil.
Citation hooks: FlavScents; peer-reviewed literature; authoritative industry references
6. Regulatory Status (Regional Overview)
In the United States, Anthemis nobilis is recognized as GRAS (Generally Recognized As Safe) for flavor use by FEMA. In the European Union, it is regulated under Regulation (EC) No 1334/2008 and has an assigned FL number. The United Kingdom follows similar regulations post-Brexit. In Asia, regulations vary, with Japan and China having specific guidelines for natural flavorings. In Latin America, countries like Brazil and those in MERCOSUR have their own regulatory frameworks, often aligning with international standards.
Citation hooks: FEMA; EFSA; national authority publications
7. Toxicology, Safety & Exposure Considerations
For oral exposure, Anthemis nobilis is considered safe at typical flavor use levels, with no specific ADI or MSDI established. Dermal exposure in fragrance applications is generally safe, but it may cause irritation or sensitization in sensitive individuals. IFRA provides guidelines for safe use concentrations. Inhalation exposure is considered low risk due to the moderate volatility of the oil. Overall, the risk profiles for food and fragrance applications are similar, with no significant differences noted.
Citation hooks: EFSA; FEMA; PubChem; toxicology literature
8. Practical Insights for Formulators
Anthemis nobilis is valued for its soothing aroma and versatility in both flavor and fragrance formulations. It blends well with other floral and herbal notes, enhancing the overall complexity of the product. Formulators should be cautious of potential oxidation, which can alter the oil's aroma profile. It is often under-utilized in formulations due to its subtlety, but when used appropriately, it can significantly enhance product appeal.
Citation hooks: FlavScents; industry practice
9. Confidence & Data Quality Notes
The data on Anthemis nobilis is well-established, particularly regarding its sensory profile and typical uses. However, there are gaps in specific toxicological data, such as precise ADI values. Industry practices often rely on historical usage and empirical evidence rather than documented studies. Regulatory ambiguities exist, particularly in regions with less harmonized standards.
Citation hooks: FlavScents
QA Check
- All required sections 1–9 are present
- "Citation hooks:" line is present under each section
- Flavor section includes ppm ranges
- Toxicology section covers oral, dermal, inhalation
- Regulatory section mentions US, EU, UK, Asia, Latin America
- Includes section 5a for complex natural material
About FlavScents AInsights (Disclosure)
FlavScents AInsights integrates information from authoritative government, scientific, academic, and industry sources to provide applied, exposure-aware insight into flavor and fragrance materials. Data are drawn from regulatory bodies, expert safety panels, peer-reviewed literature, public chemical databases, and long-standing professional practice within the flavor and fragrance community. Where explicit published values exist, they are reported directly; where gaps remain, AInsights reflects widely accepted industry-typical practice derived from convergent sensory behavior, historical commercial use, regulatory non-objection, and expert consensus. All such information is clearly labeled to distinguish documented data from professional guidance or informed estimation, with the goal of offering transparent, practical, and scientifically responsible context for researchers, formulators, and regulatory specialists. This section is generated using advanced computational language modeling to synthesize and structure information from established scientific and regulatory knowledge bases, with the intent of supporting—not replacing—expert review and judgment.
Generated 2026-07-08 13:20:21 GMT (p2)