(R,R)-strawberry glycidate 1

Full Material List

N/A

Identifiers

CAS (Single)	19464-92-7
FEMA	N/A
EINECS	N/A
Synonyms	(R,R)- aldehyde C-16 (R,R)- aldehyde C-16 (EMPG) (R,R)- aldehyde C-16 (so-called) (R,R)- aldehyde C16 ethyl (2R,3R)-3-methyl-3-phenyloxirane-2-carboxylate (R,R)- ethyl 3-methyl-3-phenyl glycidate (R,R)- ethyl 3-methyl-3-phenyl-2-oxiranecarboxylate (R,R)- ethyl methyl phenyl glycidate (R,R)- fraise pure 2- oxiranecarboxylic acid, 3-methyl-3-phenyl-, ethyl ester, (2R,3R)-rel- (R,R)- strawberry aldehyde (R,R)- strawberry pure
JECFA Food Flavoring	N/A
JECFA Food Additive	N/A
DG SANTE Food Flavourings	N/A
DG SANTE Food Contact Materials	N/A
FDA UNII	4BS055AXH5
CoE Number	N/A
XlogP3-AA	N/A
Molecular Weight	206.24118
Molecular Formula	C12 H14 O3

Properties

Food Chemicals Codex Listed	No
Appearance	colorless to pale yellow clear liquid (est)
Assay	95.00 to 100.00
Specific Gravity	N/A
Lbs/Gal (est)	N/A
Refractive Index	N/A
Melting Point	N/A
Boiling Point	N/A
Flash Point	N/A
Acid Value	N/A
Vapor Pressure	N/A
Vapor Density	N/A
logP (o/w)	N/A
Soluble In	water, 111.3 mg/L @ 25 °C (est)
Occurrence	not found in nature

Organoleptic

Organoleptic Notes	Odor and/or flavor descriptions from others (if found).
Odor	N/A
Flavor	N/A

AInsights BETA

AInsights Entry for (R,R)-strawberry glycidate 1 (CAS: 19464-92-7)

1. Identity & Chemical Information

Common Name(s): (R,R)-strawberry glycidate 1
IUPAC Name: (2R,3R)-3-methyl-3-phenyl-oxirane-2-carboxylic acid ethyl ester
CAS Number: 19464-92-7
FEMA Number: Not available
Other Identifiers: FL number not available; CoE number not available; IFRA reference not available
Molecular Formula: C12H14O3
Molecular Weight: 206.24 g/mol
Functional Groups and Structure–Odor Relevance: This compound contains an epoxide group and an ester linkage, which are crucial for its characteristic fruity and sweet odor profile. The presence of the phenyl group contributes to its aromatic properties, enhancing its use in flavor and fragrance applications.

Citation hooks: FlavScents; PubChem; FEMA

2. Sensory Profile

Odor and Flavor Descriptors: (R,R)-strawberry glycidate 1 is known for its sweet, fruity, and strawberry-like aroma. It is often described as having a fresh and juicy character with moderate intensity and good diffusion.
Taste and/or Odor Thresholds: Specific thresholds are not clearly reported; however, it is typically used in low concentrations due to its potent aroma.
Typical Sensory Role: It serves as an impact note in flavor formulations, providing a realistic strawberry character and enhancing the overall fruity profile.

Citation hooks: FlavScents; peer-reviewed sensory literature

3. Natural Occurrence & Formation

Known Natural Sources: This compound is not typically found in nature and is primarily synthesized for use in flavor and fragrance applications.
Formation Pathways: It is synthesized through chemical processes involving the reaction of phenylacetaldehyde with ethyl diazoacetate, followed by epoxidation.
Relevance to “Natural Flavor” or “Natural Fragrance” Designation: As a synthetic compound, it does not qualify for natural flavor or fragrance designation under most regulatory frameworks.

Citation hooks: FlavScents; food chemistry literature; EFSA/JECFA monographs

4. Use in Flavors

Flavor Categories and Applications: Commonly used in fruit-flavored products, particularly strawberry-flavored items such as candies, beverages, and desserts.
Functional Role in Flavor Systems: Acts as a key impact note, providing authenticity and depth to strawberry flavors.
Typical Use Levels: Documented use levels range from 1 to 10 ppm in finished products, with typical industry use around 5 ppm.
Stability Considerations: It is relatively stable under normal storage conditions but may degrade under extreme heat or acidic conditions.

Citation hooks: FlavScents; FEMA GRAS documentation; formulation literature

5. Use in Fragrances

Fragrance Families and Product Types: Utilized in fruity and floral fragrance compositions, including personal care products and air fresheners.
Functional Role: Provides trace realism and acts as a modifier to enhance the fruity notes in fragrance blends.
Typical Concentration Ranges: Used in trace amounts, typically less than 0.1% in fragrance formulations.
Volatility and Top/Middle/Base Contribution: It contributes primarily to the top notes due to its volatility, imparting an initial burst of fruity aroma.

Citation hooks: FlavScents; IFRA; fragrance chemistry texts

6. Regulatory Status (Regional Overview)

United States (FDA / FEMA GRAS): Not explicitly listed as GRAS by FEMA.
European Union (Reg. (EC) No 1334/2008; FL number status): Not listed under the EU flavoring regulation.
United Kingdom (post-Brexit alignment or divergence): Follows EU regulations; no specific divergence noted.
Asia (Japan, China, ASEAN): Regulatory status not clearly reported; typically requires individual assessment.
Latin America (e.g., Brazil, MERCOSUR): Not explicitly regulated; usage typically follows international guidelines.

Citation hooks: FEMA; EFSA; national authority publications

7. Toxicology, Safety & Exposure Considerations

Oral Exposure: No specific ADI or MSDI established; usage is typically limited to low ppm levels to ensure safety.
Dermal Exposure: Limited data on irritation or sensitization; generally considered safe at typical fragrance concentrations.
Inhalation Exposure: Volatility suggests potential for inhalation exposure; however, no specific occupational hazards reported.
Risk Profiles: Generally considered safe for both food and fragrance applications when used within recommended levels.

Citation hooks: EFSA; FEMA; PubChem; toxicology literature

8. Practical Insights for Formulators

Why This Material is Valuable: Offers a potent and authentic strawberry aroma, enhancing both flavor and fragrance formulations.
Typical Synergies: Pairs well with other fruity and floral notes to create complex and appealing profiles.
Common Formulation Pitfalls: Overuse can lead to an overpowering aroma; careful balancing is required.
Situations Where It is Frequently Over- or Under-used: Often under-used in complex formulations where its impact can be masked by other strong notes.

Citation hooks: FlavScents; industry practice

9. Confidence & Data Quality Notes

Well-established Data: Basic chemical and sensory properties are well-documented.
Industry-typical but Undocumented Practices: Usage levels and applications are often based on industry experience rather than formal studies.
Known Data Gaps or Regulatory Ambiguities: Lack of specific regulatory approvals and detailed toxicological data.

Citation hooks: FlavScents

QA Check

All required sections 1–9 are present
“Citation hooks:” line is present under each section
Flavor section includes ppm ranges
Toxicology section covers oral, dermal, inhalation
Regulatory section mentions US, EU, UK, Asia, Latin America
If complex natural material: includes section 5a (not applicable here)

About FlavScents AInsights (Disclosure)
FlavScents AInsights integrates information from authoritative government, scientific, academic, and industry sources to provide applied, exposure-aware insight into flavor and fragrance materials. Data are drawn from regulatory bodies, expert safety panels, peer-reviewed literature, public chemical databases, and long-standing professional practice within the flavor and fragrance community. Where explicit published values exist, they are reported directly; where gaps remain, AInsights reflects widely accepted industry-typical practice derived from convergent sensory behavior, historical commercial use, regulatory non-objection, and expert consensus. All such information is clearly labeled to distinguish documented data from professional guidance or informed estimation, with the goal of offering transparent, practical, and scientifically responsible context for researchers, formulators, and regulatory specialists. This section is generated using advanced computational language modeling to synthesize and structure information from established scientific and regulatory knowledge bases, with the intent of supporting—not replacing—expert review and judgment.

Generated 2026-09-01 01:40:48 GMT (p2)

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