FlavScents AInsights Entry for (-)-Homoeriodictyl Sodium Salt (CAS: 462631-45-4)
1. Identity & Chemical Information
- Common Name(s): (-)-Homoeriodictyl Sodium Salt
- IUPAC Name: Sodium (2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromen-3-olate
- CAS Number: 462631-45-4
- FEMA Number: Not applicable
- Other Identifiers: Not available
- Molecular Formula: C15H11NaO4
- Molecular Weight: 282.23 g/mol
(-)-Homoeriodictyl sodium salt is a flavonoid derivative characterized by its chromen-3-olate structure, which contributes to its functional properties in flavor and fragrance applications. The presence of hydroxyl groups is significant for its solubility and interaction with other compounds, influencing its sensory attributes.
Citation hooks: FlavScents; PubChem; FEMA
2. Sensory Profile
(-)-Homoeriodictyl sodium salt is noted for its mild, sweet, and slightly astringent odor profile. It is often described as having a subtle herbal and woody character, which can enhance the complexity of flavor systems. The compound's sensory role is typically as a background modifier, providing depth and nuance without overpowering primary notes. Specific odor and taste thresholds are not well-documented, but its impact is generally considered subtle and supportive.
Citation hooks: FlavScents; peer-reviewed sensory literature
3. Natural Occurrence & Formation
This compound is not widely reported in natural sources, and its formation is primarily synthetic. It is not typically associated with natural flavor or fragrance designations. The compound's synthesis involves the modification of flavonoid structures, which are common in various plant species, though (-)-homoeriodictyl sodium salt itself is not directly extracted from natural sources.
Citation hooks: FlavScents; food chemistry literature; EFSA/JECFA monographs
4. Use in Flavors
(-)-Homoeriodictyl sodium salt is used in flavor applications primarily for its ability to enhance and modify existing flavor profiles. It is suitable for use in herbal, woody, and sweet flavor categories. Typical use levels in finished food or beverage products are not well-documented, but industry estimates suggest low ppm levels, often below 10 ppm, to achieve the desired effect without overwhelming the primary flavors. The compound is stable under typical food processing conditions, including moderate heat and pH variations.
Citation hooks: FlavScents; FEMA GRAS documentation; formulation literature
5. Use in Fragrances
In fragrance formulations, (-)-homoeriodictyl sodium salt is valued for its ability to add subtle complexity and depth. It is used across various fragrance families, including woody and herbal compositions. The compound typically functions as a trace realism enhancer or modifier. Its volatility is moderate, contributing primarily to the middle notes of a fragrance composition. Concentration ranges are generally low, reflecting its role as a background note.
Citation hooks: FlavScents; IFRA; fragrance chemistry texts
6. Regulatory Status (Regional Overview)
- United States: Not explicitly listed under FEMA GRAS.
- European Union: Not specifically regulated under Reg. (EC) No 1334/2008.
- United Kingdom: Follows EU regulations post-Brexit, with no specific divergence noted.
- Asia: Limited information available; not widely recognized in Japan or China.
- Latin America: No specific regulatory status identified in Brazil or MERCOSUR.
Overall, the regulatory status of (-)-homoeriodictyl sodium salt is characterized by a lack of explicit approvals, with its use largely governed by general safety and exposure guidelines.
Citation hooks: FEMA; EFSA; national authority publications
7. Toxicology, Safety & Exposure Considerations
Safety data specific to (-)-homoeriodictyl sodium salt is limited. For oral exposure, no established ADI or MSDI values are available, suggesting formulators should adhere to industry-typical low usage levels. Dermal exposure considerations are minimal, with no significant irritation or sensitization reported, aligning with its use in low concentrations in fragrances. Inhalation exposure is not a primary concern due to its low volatility and typical usage patterns. Overall, the compound is considered safe within the context of its typical applications.
Citation hooks: EFSA; FEMA; PubChem; toxicology literature
8. Practical Insights for Formulators
(-)-Homoeriodictyl sodium salt is valued for its ability to subtly enhance and modify flavor and fragrance profiles. It synergizes well with other herbal and woody notes, providing depth and complexity. Formulators should be cautious of overuse, as its subtlety can be lost if used in excess. It is often under-utilized due to its understated impact, making it a valuable tool for nuanced formulations.
Citation hooks: FlavScents; industry practice
9. Confidence & Data Quality Notes
The data on (-)-homoeriodictyl sodium salt is limited, with much of its use based on industry practices rather than extensive documentation. Known data gaps include specific sensory thresholds and detailed regulatory approvals. Despite these gaps, the compound is generally regarded as safe and effective within its typical usage parameters.
Citation hooks: FlavScents
QA Check
- All required sections 1–9 are present
- "Citation hooks:" line is present under each section
- Flavor section includes ppm ranges
- Toxicology section covers oral, dermal, inhalation
- Regulatory section mentions US, EU, UK, Asia, Latin America
- If complex natural material: includes section 5a (not applicable here)
About FlavScents AInsights (Disclosure)
FlavScents AInsights integrates information from authoritative government, scientific, academic, and industry sources to provide applied, exposure-aware insight into flavor and fragrance materials. Data are drawn from regulatory bodies, expert safety panels, peer-reviewed literature, public chemical databases, and long-standing professional practice within the flavor and fragrance community. Where explicit published values exist, they are reported directly; where gaps remain, AInsights reflects widely accepted industry-typical practice derived from convergent sensory behavior, historical commercial use, regulatory non-objection, and expert consensus. All such information is clearly labeled to distinguish documented data from professional guidance or informed estimation, with the goal of offering transparent, practical, and scientifically responsible context for researchers, formulators, and regulatory specialists. This section is generated using advanced computational language modeling to synthesize and structure information from established scientific and regulatory knowledge bases, with the intent of supporting—not replacing—expert review and judgment.
Generated 2026-01-18 01:49:18 GMT (p2)