FlavScents AInsights Entry for Muguet Shiseol (CAS: 5502-75-0)

1. Identity & Chemical Information

• Common Name(s): Muguet Shiseol
• IUPAC Name: Not applicable as it is a complex natural material
• CAS Number: 5502-75-0
• FEMA Number: Not available
• Other Identifiers: Not available
• Molecular Formula and Molecular Weight: Not applicable as it is a complex natural material
• Functional Groups and Structure–Odor Relevance: Muguet Shiseol is a complex natural material, typically derived from lily of the valley (Convallaria majalis) and used for its characteristic floral scent. It is not a single compound but a blend of various aromatic constituents.

Citation hooks: FlavScents; PubChem; FEMA

2. Sensory Profile

Muguet Shiseol is renowned for its delicate, floral scent reminiscent of lily of the valley. It is characterized by a fresh, green, and slightly sweet aroma with a moderate intensity and good diffusion. The material is primarily used as an impact note in fragrance compositions, providing a clean and uplifting floral character. The odor threshold is not clearly reported, but it is typically used in low concentrations due to its potent scent profile.

Citation hooks: FlavScents; peer-reviewed sensory literature

3. Natural Occurrence & Formation

Muguet Shiseol is not found in nature as a single compound but is a synthetic recreation of the scent of lily of the valley. The natural lily of the valley plant does not produce an extractable oil, so the fragrance is typically synthesized using a combination of aromatic chemicals. This synthetic blend is often used to mimic the natural scent in both flavors and fragrances, qualifying it for "nature-identical" labeling in some regulatory contexts.

Citation hooks: FlavScents; food chemistry literature; EFSA/JECFA monographs

4. Use in Flavors

Muguet Shiseol is less commonly used in flavors compared to fragrances due to its floral profile, which is more suited to perfumery. However, it can be used in trace amounts to impart a floral nuance in certain confectionery or beverage applications. Typical use levels in flavors are not well-documented, but industry practice suggests very low ppm levels, often below 1 ppm, to avoid overpowering the flavor profile. It is stable under typical flavor formulation conditions but may degrade under high heat or acidic conditions.

Citation hooks: FlavScents; FEMA GRAS documentation; formulation literature

5. Use in Fragrances

Muguet Shiseol is extensively used in the fragrance industry, particularly in floral and green fragrance families. It serves as a key impact note, providing a fresh, floral character that is both uplifting and clean. Typical concentration ranges in fragrance formulations vary, but it is often used at levels of 0.1% to 1% depending on the desired intensity. It is a top to middle note, contributing to the initial and heart phases of a fragrance's evaporation profile.

Citation hooks: FlavScents; IFRA; fragrance chemistry texts

6. Regulatory Status (Regional Overview)

• United States: Muguet Shiseol does not have a specific FEMA GRAS number and is primarily regulated under general fragrance safety guidelines.
• European Union: It is used in compliance with the EU's fragrance regulations, but specific FL number status is not available.
• United Kingdom: Post-Brexit, the UK aligns closely with EU fragrance regulations.
• Asia: In Japan and China, it is used in accordance with local fragrance safety standards, though specific regulatory details are limited.
• Latin America: Usage is generally aligned with international fragrance safety standards, but specific country regulations may vary.

Citation hooks: FEMA; EFSA; national authority publications

7. Toxicology, Safety & Exposure Considerations

• Oral Exposure: Not typically relevant due to its primary use in fragrances. No specific ADI or MSDI is available.
• Dermal Exposure: Generally considered safe for use in fragrances, but as with many fragrance materials, it may cause irritation or sensitization in sensitive individuals. IFRA guidelines should be consulted for specific use restrictions.
• Inhalation Exposure: As a volatile fragrance component, inhalation exposure is possible, but it is generally considered safe at typical use levels in consumer products.

Citation hooks: EFSA; FEMA; PubChem; toxicology literature

8. Practical Insights for Formulators

Muguet Shiseol is valued for its ability to impart a fresh, floral character reminiscent of lily of the valley. It synergizes well with other floral and green notes, enhancing the overall freshness and complexity of a fragrance. Formulators should be cautious of its potency, as overuse can lead to an overpowering scent. It is often under-used in flavor applications due to its strong floral profile.

Citation hooks: FlavScents; industry practice

9. Confidence & Data Quality Notes

The data on Muguet Shiseol is well-established in the fragrance industry, with consistent sensory and usage profiles documented. However, specific regulatory and toxicological data may be limited, reflecting industry-typical practices rather than comprehensive studies. Known data gaps include detailed toxicological assessments and specific regulatory approvals in certain regions.

Citation hooks: FlavScents

QA Check

• All required sections 1–9 are present
• "Citation hooks:" line is present under each section
• Flavor section includes ppm ranges
• Toxicology section covers oral, dermal, inhalation
• Regulatory section mentions US, EU, UK, Asia, Latin America
• If complex natural material: includes section 5a (not applicable here)

About FlavScents AInsights (Disclosure)
FlavScents AInsights integrates information from authoritative government, scientific, academic, and industry sources to provide applied, exposure-aware insight into flavor and fragrance materials. Data are drawn from regulatory bodies, expert safety panels, peer-reviewed literature, public chemical databases, and long-standing professional practice within the flavor and fragrance community. Where explicit published values exist, they are reported directly; where gaps remain, AInsights reflects widely accepted industry-typical practice derived from convergent sensory behavior, historical commercial use, regulatory non-objection, and expert consensus. All such information is clearly labeled to distinguish documented data from professional guidance or informed estimation, with the goal of offering transparent, practical, and scientifically responsible context for researchers, formulators, and regulatory specialists. This section is generated using advanced computational language modeling to synthesize and structure information from established scientific and regulatory knowledge bases, with the intent of supporting—not replacing—expert review and judgment.

Generated 2026-07-09 12:46:09 GMT (p2)