FlavScents AInsights Entry: Ascorbic Acid (CAS: 50-81-7)
1. Identity & Chemical Information
- Common Name(s): Ascorbic Acid, Vitamin C
- IUPAC Name: (5R)-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one
- CAS Number: 50-81-7
- FEMA Number: 2109
- Other Identifiers: FL No. 04.001, EINECS No. 200-066-2
- Molecular Formula: C6H8O6
- Molecular Weight: 176.12 g/mol
- Functional Groups and Structure-Odor Relevance: Ascorbic acid contains multiple hydroxyl groups, contributing to its solubility and reactivity. Its structure is not directly related to odor but is crucial for its antioxidant properties.
Citation hooks: FlavScents; PubChem; FEMA
2. Sensory Profile
Ascorbic acid is primarily recognized for its sour taste, which is sharp and refreshing. It is often used to enhance the tartness in food and beverage formulations. The intensity of its sourness can vary depending on concentration, with a typical taste threshold around 2-3 ppm. Ascorbic acid does not contribute significantly to odor but can influence the overall sensory profile by modifying other flavors.
Citation hooks: FlavScents; peer-reviewed sensory literature
3. Natural Occurrence & Formation
Ascorbic acid is naturally found in a variety of fruits and vegetables, including citrus fruits, strawberries, kiwi, and bell peppers. It is biosynthesized in plants and some animals through the conversion of glucose. In the context of "natural flavor" designation, ascorbic acid is often derived from natural sources or synthesized to mimic its natural counterpart.
Citation hooks: FlavScents; food chemistry literature; EFSA/JECFA monographs
4. Use in Flavors
Ascorbic acid is widely used in flavor formulations to enhance tartness and stabilize color. It is commonly used in beverages, candies, and fruit-flavored products. Typical use levels range from 50 to 200 ppm in finished products, with higher concentrations used in specific applications like vitamin supplements. Ascorbic acid is stable under acidic conditions but can degrade with heat and exposure to light and oxygen.
Citation hooks: FlavScents; FEMA GRAS documentation; formulation literature
5. Use in Fragrances
While not a primary fragrance component, ascorbic acid can be used in fragrance formulations as an antioxidant to prevent oxidation of volatile compounds. It does not contribute directly to the fragrance profile but supports the stability and longevity of the fragrance. Its volatility is low, and it does not contribute to the top, middle, or base notes.
Citation hooks: FlavScents; IFRA; fragrance chemistry texts
6. Regulatory Status (Regional Overview)
- United States: Ascorbic acid is recognized as GRAS (Generally Recognized As Safe) by the FDA and FEMA for use in food.
- European Union: Approved as a food additive (E300) under Regulation (EC) No 1333/2008.
- United Kingdom: Follows EU regulations post-Brexit, with no significant divergence.
- Asia: Widely accepted in countries like Japan and China as a food additive.
- Latin America: Generally approved across MERCOSUR countries, including Brazil.
Citation hooks: FEMA; EFSA; national authority publications
7. Toxicology, Safety & Exposure Considerations
Ascorbic acid is considered safe for oral consumption with an established ADI (Acceptable Daily Intake) of "not specified" due to its low toxicity. Dermal exposure is generally safe, with minimal risk of irritation or sensitization. Inhalation exposure is not a typical concern due to its low volatility. The risk profile is consistent across food and fragrance applications, with no significant differences.
Citation hooks: EFSA; FEMA; PubChem; toxicology literature
8. Practical Insights for Formulators
Ascorbic acid is valued for its dual role as a flavor enhancer and antioxidant. It synergizes well with other acids like citric acid to enhance tartness. Formulators should be cautious of its instability in high heat and light conditions, which can lead to degradation. It is often under-used in formulations where its antioxidant properties could extend product shelf life.
Citation hooks: FlavScents; industry practice
9. Confidence & Data Quality Notes
The data on ascorbic acid is well-established, with extensive documentation in both scientific literature and regulatory frameworks. Industry practices are well-documented, though some variability exists in use levels across different applications. No significant data gaps or regulatory ambiguities are noted.
Citation hooks: FlavScents
QA Check
- All required sections 1-9 are present
- "Citation hooks:" line is present under each section
- Flavor section includes ppm ranges
- Toxicology section covers oral, dermal, inhalation
- Regulatory section mentions US, EU, UK, Asia, Latin America
- If complex natural material: includes section 5a (not applicable here)
About FlavScents AInsights (Disclosure)
FlavScents AInsights integrates information from authoritative government, scientific, academic, and industry sources to provide applied, exposure-aware insight into flavor and fragrance materials. Data are drawn from regulatory bodies, expert safety panels, peer-reviewed literature, public chemical databases, and long-standing professional practice within the flavor and fragrance community. Where explicit published values exist, they are reported directly; where gaps remain, AInsights reflects widely accepted industry-typical practice derived from convergent sensory behavior, historical commercial use, regulatory non-objection, and expert consensus. All such information is clearly labeled to distinguish documented data from professional guidance or informed estimation, with the goal of offering transparent, practical, and scientifically responsible context for researchers, formulators, and regulatory specialists. This section is generated using advanced computational language modeling to synthesize and structure information from established scientific and regulatory knowledge bases, with the intent of supporting—not replacing—expert review and judgment.
Generated 2026-02-20 13:09:26 GMT (p2)