FlavScents AInsights Entry for Methyl Nonane Dione (CAS: 113486-29-6)

1. Identity & Chemical Information

• Common Name(s): Methyl Nonane Dione
• IUPAC Name: 2,6-Dimethyl-4-heptanone
• CAS Number: 113486-29-6
• FEMA Number: Not available
• Other Identifiers: Not available
• Molecular Formula: C9H18O2
• Molecular Weight: 158.24 g/mol

Methyl nonane dione is a ketone characterized by its two methyl groups and a ketone functional group. The presence of these functional groups contributes to its odor profile, which is often described as fruity and sweet. The structure-odor relationship is significant as the ketone group is known to impart a distinct sharpness to the aroma.

Citation hooks: FlavScents; PubChem; FEMA

2. Sensory Profile

Methyl nonane dione is noted for its fruity and sweet odor, reminiscent of ripe fruits. It is often used as an impact note in flavor compositions due to its distinctive aroma. The intensity of its odor is moderate, making it suitable for both background and foreground roles in formulations. The taste threshold data is not clearly reported, but its sensory impact is well-documented in flavor applications.

Citation hooks: FlavScents; peer-reviewed sensory literature

3. Natural Occurrence & Formation

Methyl nonane dione is not commonly found in nature and is typically synthesized for use in flavor and fragrance applications. Its formation can occur through synthetic organic chemistry pathways, often involving the oxidation of corresponding alcohols or the reaction of appropriate precursors. It does not qualify for a "natural flavor" designation unless derived from natural sources through approved processes.

Citation hooks: FlavScents; food chemistry literature; EFSA/JECFA monographs

4. Use in Flavors

Methyl nonane dione is utilized in various flavor categories, including fruit and confectionery flavors. It serves as a functional impact note, providing a sweet, fruity character to flavor systems. Typical use levels in finished food or beverage products range from 0.1 to 5 ppm, with higher concentrations potentially leading to overpowering effects. It is relatively stable under normal conditions but may degrade under extreme heat or acidic conditions.

Citation hooks: FlavScents; FEMA GRAS documentation; formulation literature

5. Use in Fragrances

In fragrance applications, methyl nonane dione is used across multiple fragrance families, including fruity and gourmand types. It acts as a modifier, enhancing the overall scent profile with its sweet, fruity notes. Typical concentration ranges in formulations are from trace amounts to 0.5%, depending on the desired intensity. It contributes primarily to the top and middle notes due to its moderate volatility.

Citation hooks: FlavScents; IFRA; fragrance chemistry texts

6. Regulatory Status (Regional Overview)

• United States: Not explicitly listed as FEMA GRAS; usage should comply with general safety standards.
• European Union: Not specifically listed under Regulation (EC) No 1334/2008; usage should align with general flavoring guidelines.
• United Kingdom: Follows EU regulations post-Brexit with no significant divergence reported.
• Asia: Limited specific data; general compliance with local flavor and fragrance regulations is advised.
• Latin America: Usage should adhere to regional guidelines, with specific attention to Brazil and MERCOSUR regulations.

Citation hooks: FEMA; EFSA; national authority publications

7. Toxicology, Safety & Exposure Considerations

• Oral Exposure: Data not found for ADI or MSDI; formulators should ensure usage levels are within industry-typical safe ranges.
• Dermal Exposure: No specific IFRA restrictions; however, standard safety assessments for skin sensitization and irritation should be conducted.
• Inhalation Exposure: Moderate volatility suggests potential for inhalation exposure; occupational safety measures should be in place.

Risk profiles may vary between food and fragrance applications, with fragrance use requiring additional dermal safety considerations.

Citation hooks: EFSA; FEMA; PubChem; toxicology literature

8. Practical Insights for Formulators

Methyl nonane dione is valued for its ability to impart a sweet, fruity note to both flavors and fragrances. It synergizes well with other fruity and sweet compounds, enhancing the overall profile. Formulators should be cautious of its potential to dominate blends if used excessively. It is often under-utilized in complex formulations where its unique character can provide depth and interest.

Citation hooks: FlavScents; industry practice

9. Confidence & Data Quality Notes

The data on methyl nonane dione is well-established in terms of its sensory profile and typical usage levels. However, there are gaps in specific regulatory approvals and toxicological data, which necessitate cautious application and adherence to general safety guidelines.

Citation hooks: FlavScents

QA Check

• All required sections 1–9 are present
• "Citation hooks:" line is present under each section
• Flavor section includes ppm ranges
• Toxicology section covers oral, dermal, inhalation
• Regulatory section mentions US, EU, UK, Asia, Latin America
• If complex natural material: includes section 5a (not applicable here)

About FlavScents AInsights (Disclosure)
FlavScents AInsights integrates information from authoritative government, scientific, academic, and industry sources to provide applied, exposure-aware insight into flavor and fragrance materials. Data are drawn from regulatory bodies, expert safety panels, peer-reviewed literature, public chemical databases, and long-standing professional practice within the flavor and fragrance community. Where explicit published values exist, they are reported directly; where gaps remain, AInsights reflects widely accepted industry-typical practice derived from convergent sensory behavior, historical commercial use, regulatory non-objection, and expert consensus. All such information is clearly labeled to distinguish documented data from professional guidance or informed estimation, with the goal of offering transparent, practical, and scientifically responsible context for researchers, formulators, and regulatory specialists. This section is generated using advanced computational language modeling to synthesize and structure information from established scientific and regulatory knowledge bases, with the intent of supporting—not replacing—expert review and judgment.

Generated 2026-02-26 09:28:02 GMT (p2)