FlavScents AInsights Entry for Methyl Eugenol (CAS: 93-15-2)
1. Identity & Chemical Information
Methyl eugenol is a naturally occurring phenylpropene, commonly found in various essential oils. Its IUPAC name is 1,2-dimethoxy-4-(prop-2-en-1-yl)benzene. The CAS number for methyl eugenol is 93-15-2. It is identified by FEMA number 2473. Other identifiers include FL number 12.007 and CoE number 206. The molecular formula is C11H14O2, with a molecular weight of 178.23 g/mol. Methyl eugenol contains methoxy groups and an allyl side chain, contributing to its characteristic sweet, spicy, and clove-like odor.
Citation hooks: FlavScents; PubChem; FEMA
2. Sensory Profile
Methyl eugenol is known for its sweet, spicy, and clove-like aroma, often described as warm and slightly floral. It has a moderate intensity and good diffusion, making it a versatile component in both flavor and fragrance formulations. The odor threshold is relatively low, allowing it to impart a noticeable impact even at low concentrations. In sensory applications, it serves as an impact note and can enhance the overall realism of a composition.
Citation hooks: FlavScents; peer-reviewed sensory literature
3. Natural Occurrence & Formation
Methyl eugenol is found in a variety of essential oils, including basil, bay, and clove oils. It is biosynthesized in plants through the shikimate pathway, where it serves as a defense compound against herbivores and pathogens. Its presence in natural sources qualifies it for use in "natural flavor" and "natural fragrance" designations, provided it is derived from these sources.
Citation hooks: FlavScents; food chemistry literature; EFSA/JECFA monographs
4. Use in Flavors
Methyl eugenol is used in flavor formulations for its sweet and spicy notes, commonly found in spice, floral, and fruity flavor categories. It acts as a flavor enhancer and can be used to add depth and complexity to a formulation. Typical use levels in food and beverages range from 0.1 to 10 ppm, depending on the desired intensity and application. It is relatively stable under normal processing conditions but may degrade under high heat or acidic conditions.
Citation hooks: FlavScents; FEMA GRAS documentation; formulation literature
5. Use in Fragrances
In fragrance applications, methyl eugenol is used across various fragrance families, including oriental, floral, and spicy compositions. It serves as a modifier and impact note, providing warmth and depth. Typical concentration ranges in perfumes are from trace amounts up to 0.5%, depending on the formulation. Methyl eugenol contributes primarily to the middle notes due to its moderate volatility.
Citation hooks: FlavScents; IFRA; fragrance chemistry texts
6. Regulatory Status (Regional Overview)
In the United States, methyl eugenol is not generally recognized as safe (GRAS) for flavor use by FEMA. In the European Union, it is subject to restrictions under Regulation (EC) No 1334/2008 due to potential health concerns. The UK follows similar regulations post-Brexit. In Asia, regulations vary, with some countries imposing strict limits on its use. In Latin America, countries like Brazil and those in MERCOSUR have specific guidelines for its use in flavors and fragrances.
Citation hooks: FEMA; EFSA; national authority publications
7. Toxicology, Safety & Exposure Considerations
Methyl eugenol has been associated with potential carcinogenic effects in animal studies, leading to restrictions in its use. Oral exposure through flavor use is limited due to these concerns, with no established acceptable daily intake (ADI). Dermal exposure in fragrances is also restricted, with IFRA setting limits to minimize sensitization and irritation risks. Inhalation exposure is considered low risk due to its moderate volatility, but occupational exposure should be monitored.
Citation hooks: EFSA; FEMA; PubChem; toxicology literature
8. Practical Insights for Formulators
Methyl eugenol is valued for its ability to impart warmth and complexity to both flavors and fragrances. It synergizes well with other spicy and floral notes but should be used cautiously due to regulatory restrictions. Common pitfalls include overuse, leading to regulatory non-compliance, and potential sensory imbalance. It is often under-utilized in formulations seeking a natural profile due to its natural occurrence.
Citation hooks: FlavScents; industry practice
9. Confidence & Data Quality Notes
Data on methyl eugenol is well-established, particularly regarding its sensory characteristics and regulatory status. However, industry practices may vary, and formulators should verify compliance with regional regulations. Known data gaps include comprehensive human exposure studies, necessitating cautious use in consumer products.
Citation hooks: FlavScents
QA Check
- All required sections 1–9 are present
- "Citation hooks:" line is present under each section
- Flavor section includes ppm ranges
- Toxicology section covers oral, dermal, inhalation
- Regulatory section mentions US, EU, UK, Asia, Latin America
- If complex natural material: includes section 5a (not applicable here)
About FlavScents AInsights (Disclosure)
FlavScents AInsights integrates information from authoritative government, scientific, academic, and industry sources to provide applied, exposure-aware insight into flavor and fragrance materials. Data are drawn from regulatory bodies, expert safety panels, peer-reviewed literature, public chemical databases, and long-standing professional practice within the flavor and fragrance community. Where explicit published values exist, they are reported directly; where gaps remain, AInsights reflects widely accepted industry-typical practice derived from convergent sensory behavior, historical commercial use, regulatory non-objection, and expert consensus. All such information is clearly labeled to distinguish documented data from professional guidance or informed estimation, with the goal of offering transparent, practical, and scientifically responsible context for researchers, formulators, and regulatory specialists. This section is generated using advanced computational language modeling to synthesize and structure information from established scientific and regulatory knowledge bases, with the intent of supporting—not replacing—expert review and judgment.
Generated 2026-08-29 09:55:17 GMT (p2)