FlavScents AInsights Entry: Methyl Dihydrojasmonate (CAS: 24851-98-7)

1. Identity & Chemical Information

• Common Name(s): Methyl dihydrojasmonate, Hedione
• IUPAC Name: Methyl 2-(3-oxo-2-pentylcyclopentyl)acetate
• CAS Number: 24851-98-7
• FEMA Number: 3496
• Other Identifiers: FL No. 09.779, CoE No. 135
• Molecular Formula: C13H22O3
• Molecular Weight: 226.31 g/mol

Methyl dihydrojasmonate is a synthetic compound characterized by its cyclopentanone structure with an ester functional group. This structure is crucial for its odor profile, contributing to its jasmine-like scent, which is widely appreciated in both flavor and fragrance applications.

Citation hooks: FlavScents; PubChem; FEMA

2. Sensory Profile

Methyl dihydrojasmonate is renowned for its delicate, floral aroma reminiscent of jasmine, with a fresh, green undertone. It is often described as having a moderate intensity and excellent diffusion properties, making it a versatile component in perfumery. The compound serves as an impact note in fragrance compositions, providing a naturalistic floral character. Odor thresholds are typically low, enhancing its effectiveness even at minimal concentrations.

Citation hooks: FlavScents; peer-reviewed sensory literature

3. Natural Occurrence & Formation

Methyl dihydrojasmonate does not occur naturally but is synthesized for use in flavors and fragrances. It is structurally related to jasmonic acid derivatives found in jasmine flowers, which are part of the plant's natural defense mechanisms. Its synthetic production allows for consistent quality and availability, supporting its designation as a "nature-identical" compound in flavor and fragrance formulations.

Citation hooks: FlavScents; food chemistry literature; EFSA/JECFA monographs

4. Use in Flavors

In flavor applications, methyl dihydrojasmonate is used to impart a floral, jasmine-like note, enhancing the complexity and realism of fruit and floral flavors. It is commonly used in categories such as beverages, confectionery, and dairy products. Typical use levels range from 0.1 to 5 ppm in finished products, with stability considerations including moderate resistance to heat and pH variations. These levels are industry-typical and should be verified for specific formulations.

Citation hooks: FlavScents; FEMA GRAS documentation; formulation literature

5. Use in Fragrances

Methyl dihydrojasmonate is a staple in the fragrance industry, used across various fragrance families, including floral, chypre, and fougère. It acts as a modifier and impact note, contributing to the top and middle notes of a fragrance composition. Typical concentrations range from 0.1% to 10% in finished products, depending on the desired intensity and diffusion. Its volatility is moderate, allowing it to blend seamlessly with other fragrance components.

Citation hooks: FlavScents; IFRA; fragrance chemistry texts

6. Regulatory Status (Regional Overview)

• United States: Recognized as GRAS by FEMA for flavor use.
• European Union: Approved under Regulation (EC) No 1334/2008 with FL No. 09.779.
• United Kingdom: Aligns with EU regulations post-Brexit.
• Asia: Approved for use in Japan and China, with specific concentration limits.
• Latin America: Generally accepted, with specific regulations in Brazil and MERCOSUR countries.

Explicit approvals and harmonized assumptions are prevalent, though formulators should verify country-specific regulations due to potential variability.

Citation hooks: FEMA; EFSA; national authority publications

7. Toxicology, Safety & Exposure Considerations

For oral exposure, methyl dihydrojasmonate is considered safe within the established FEMA GRAS limits, with no specific ADI or MSDI reported. Dermal exposure in fragrance applications is generally safe, with low irritation and sensitization potential, as supported by IFRA guidelines. Inhalation exposure is minimal due to its moderate volatility, but occupational safety measures should be observed in manufacturing settings. Risk profiles are consistent across food and fragrance applications.

Citation hooks: EFSA; FEMA; PubChem; toxicology literature

8. Practical Insights for Formulators

Methyl dihydrojasmonate is valued for its ability to impart a naturalistic floral character, enhancing both flavors and fragrances. It synergizes well with other floral and green notes, but care should be taken to avoid overuse, which can lead to an overpowering scent. It is frequently under-utilized in complex formulations where its subtlety can enhance overall composition without dominating.

Citation hooks: FlavScents; industry practice

9. Confidence & Data Quality Notes

Data on methyl dihydrojasmonate is well-established, with comprehensive sensory and regulatory information available. Industry practices are well-documented, though specific numeric values for certain applications may require further verification. Known data gaps are minimal, with ongoing research supporting its continued use.

Citation hooks: FlavScents

QA Check

• All required sections 1–9 are present
• "Citation hooks:" line is present under each section
• Flavor section includes ppm ranges
• Toxicology section covers oral, dermal, inhalation
• Regulatory section mentions US, EU, UK, Asia, Latin America
• If complex natural material: includes section 5a (not applicable here)

About FlavScents AInsights (Disclosure)
FlavScents AInsights integrates information from authoritative government, scientific, academic, and industry sources to provide applied, exposure-aware insight into flavor and fragrance materials. Data are drawn from regulatory bodies, expert safety panels, peer-reviewed literature, public chemical databases, and long-standing professional practice within the flavor and fragrance community. Where explicit published values exist, they are reported directly; where gaps remain, AInsights reflects widely accepted industry-typical practice derived from convergent sensory behavior, historical commercial use, regulatory non-objection, and expert consensus. All such information is clearly labeled to distinguish documented data from professional guidance or informed estimation, with the goal of offering transparent, practical, and scientifically responsible context for researchers, formulators, and regulatory specialists. This section is generated using advanced computational language modeling to synthesize and structure information from established scientific and regulatory knowledge bases, with the intent of supporting—not replacing—expert review and judgment.

Generated 2026-01-26 07:31:39 GMT (p2)