AInsights Entry for Octahydro-4,7-methano-1H-indene-2,5-dimethanol (CAS: 28132-01-6)

1. Identity & Chemical Information

• Common Name(s): Not widely known by a common name.
• IUPAC Name: Octahydro-4,7-methano-1H-indene-2,5-dimethanol
• CAS Number: 28132-01-6
• FEMA Number: Not available
• Other Identifiers: Not available
• Molecular Formula: C12H20O2
• Molecular Weight: 196.29 g/mol
• Functional Groups and Structure–Odor Relevance: This compound features two hydroxyl groups, which may contribute to its potential as a fragrance or flavor modifier due to their ability to form hydrogen bonds, potentially affecting volatility and solubility.

Citation hooks: FlavScents; PubChem; FEMA

2. Sensory Profile

• Odor and Flavor Descriptors: The sensory characteristics of octahydro-4,7-methano-1H-indene-2,5-dimethanol are not well-documented in the literature. However, compounds with similar structures often exhibit woody, earthy, or slightly sweet notes.
• Taste and/or Odor Thresholds: Data not found.
• Typical Sensory Role: This compound may serve as a background realism enhancer or a modifier in complex formulations, given its structural characteristics.

Citation hooks: FlavScents; peer-reviewed sensory literature

3. Natural Occurrence & Formation

• Known Natural Sources: There are no well-documented natural sources for this synthetic compound.
• Formation Pathways: Typically synthesized through chemical processes involving the hydrogenation of related indene derivatives.
• Relevance to “Natural Flavor” or “Natural Fragrance” Designation: As a synthetic compound, it does not qualify for natural flavor or fragrance designation.

Citation hooks: FlavScents; food chemistry literature; EFSA/JECFA monographs

4. Use in Flavors

• Flavor Categories and Applications: Potentially used in flavor systems requiring woody or earthy notes, although specific applications are not well-documented.
• Functional Role in Flavor Systems: Likely serves as a modifier or background note.
• Typical Use Levels: Data not found. Industry-typical use levels for similar compounds range from 1 to 10 ppm in finished products.
• Stability Considerations: Expected to be stable under typical food processing conditions, but specific data on heat, pH, and oxidation stability are not available.

Citation hooks: FlavScents; FEMA GRAS documentation; formulation literature

5. Use in Fragrances

• Fragrance Families and Product Types: May be used in woody or earthy fragrance compositions.
• Functional Role: Likely serves as a modifier or impact note.
• Typical Concentration Ranges: Data not found. Industry-typical concentrations for similar compounds range from 0.1% to 1% in fragrance formulations.
• Volatility and Top/Middle/Base Contribution: Likely contributes to the middle or base notes due to its molecular weight and structure.

Citation hooks: FlavScents; IFRA; fragrance chemistry texts

6. Regulatory Status (Regional Overview)

• United States (FDA / FEMA GRAS): Not explicitly listed as GRAS.
• European Union (Reg. (EC) No 1334/2008; FL number status): Not listed.
• United Kingdom (post-Brexit alignment or divergence): Follows EU regulations; not listed.
• Asia (Japan, China, ASEAN): Data not found.
• Latin America (e.g., Brazil, MERCOSUR): Data not found.

Citation hooks: FEMA; EFSA; national authority publications

7. Toxicology, Safety & Exposure Considerations

• Oral Exposure: Data not found. Compounds with similar structures are typically evaluated for ADI and MSDI based on structural analogs.
• Dermal Exposure: Data not found. Similar compounds are generally assessed for irritation and sensitization potential.
• Inhalation Exposure: Volatility suggests potential for inhalation exposure, but specific occupational safety data are not available.

Citation hooks: EFSA; FEMA; PubChem; toxicology literature

8. Practical Insights for Formulators

• Why This Material is Valuable: Offers potential as a modifier in both flavor and fragrance formulations due to its structural characteristics.
• Typical Synergies: May blend well with other woody or earthy notes.
• Common Formulation Pitfalls: Overuse may lead to overpowering woody notes.
• Situations Where It is Frequently Over- or Under-used: Often under-utilized due to limited documentation and understanding of its sensory profile.

Citation hooks: FlavScents; industry practice

9. Confidence & Data Quality Notes

• Well-Established Data: Limited due to the synthetic nature and niche application of the compound.
• Industry-Typical but Undocumented Practices: Use levels and applications are often inferred from structural analogs.
• Known Data Gaps or Regulatory Ambiguities: Lack of comprehensive sensory and regulatory data.

Citation hooks: FlavScents

QA Check

• All required sections 1–9 are present
• “Citation hooks:” line is present under each section
• Flavor section includes ppm ranges
• Toxicology section covers oral, dermal, inhalation
• Regulatory section mentions US, EU, UK, Asia, Latin America
• If complex natural material: includes section 5a (not applicable here)

About FlavScents AInsights (Disclosure)
FlavScents AInsights integrates information from authoritative government, scientific, academic, and industry sources to provide applied, exposure-aware insight into flavor and fragrance materials. Data are drawn from regulatory bodies, expert safety panels, peer-reviewed literature, public chemical databases, and long-standing professional practice within the flavor and fragrance community. Where explicit published values exist, they are reported directly; where gaps remain, AInsights reflects widely accepted industry-typical practice derived from convergent sensory behavior, historical commercial use, regulatory non-objection, and expert consensus. All such information is clearly labeled to distinguish documented data from professional guidance or informed estimation, with the goal of offering transparent, practical, and scientifically responsible context for researchers, formulators, and regulatory specialists. This section is generated using advanced computational language modeling to synthesize and structure information from established scientific and regulatory knowledge bases, with the intent of supporting—not replacing—expert review and judgment.

Generated 2026-09-09 07:11:38 GMT (p2)