FlavScents AInsights Entry for Neocaspirene (CAS: 89079-92-5)

1. Identity & Chemical Information

Neocaspirene is a synthetic fragrance compound known for its unique scent profile. The IUPAC name for neocaspirene is not widely documented, but it is recognized by its CAS number 89079-92-5. Currently, there is no FEMA number assigned to neocaspirene. Other identifiers such as FL number, CoE number, or IFRA reference are not clearly reported in available literature. The molecular formula and molecular weight are not explicitly documented, which is common for some synthetic fragrance compounds. Neocaspirene's structure is characterized by functional groups that contribute to its distinctive odor profile, although specific details on structure-odor relevance are limited.

Citation hooks: FlavScents; PubChem; FEMA

2. Sensory Profile

Neocaspirene is noted for its complex sensory profile, often described as having a fresh, woody, and slightly spicy aroma. It is used in perfumery to impart a natural, earthy character to fragrance compositions. The intensity of neocaspirene is moderate, providing a balanced diffusion that complements other fragrance notes. Specific odor and taste thresholds are not well-documented, but it is typically used as an impact note in fragrance formulations, enhancing the overall sensory experience.

Citation hooks: FlavScents; peer-reviewed sensory literature

3. Natural Occurrence & Formation

Neocaspirene does not occur naturally and is synthesized for use in fragrance applications. As a synthetic compound, it does not have natural sources or formation pathways like Maillard reaction or fermentation. Its designation as a "natural fragrance" is not applicable, as it is not derived from natural sources. The synthesis of neocaspirene is tailored to achieve its specific olfactory characteristics, making it a valuable component in creating complex fragrance profiles.

Citation hooks: FlavScents; food chemistry literature; EFSA/JECFA monographs

4. Use in Flavors

Neocaspirene is primarily used in fragrance applications rather than flavors, and its use in flavor systems is not well-documented. As such, typical use levels in food or beverage applications are not available. If used, formulators should verify its suitability and safety for flavor applications, considering stability factors such as heat, pH, and oxidation. Industry-typical practices suggest cautious use, ensuring compliance with relevant safety and regulatory guidelines.

Citation hooks: FlavScents; FEMA GRAS documentation; formulation literature

5. Use in Fragrances

Neocaspirene is widely used in various fragrance families, including woody, spicy, and oriental compositions. It serves as a modifier and impact note, providing depth and complexity to fragrance products such as perfumes, colognes, and personal care items. Typical concentration ranges are not explicitly documented, but it is generally used in trace amounts to achieve the desired olfactory effect. Neocaspirene contributes primarily to the middle notes of a fragrance, offering moderate volatility and a lasting scent profile.

Citation hooks: FlavScents; IFRA; fragrance chemistry texts

6. Regulatory Status (Regional Overview)

In the United States, neocaspirene's regulatory status for fragrance use is not explicitly detailed in FEMA GRAS listings. In the European Union, it is subject to the general provisions of Regulation (EC) No 1334/2008, although specific FL number status is not reported. Post-Brexit, the United Kingdom's regulatory alignment or divergence is not clearly documented. In Asia, including Japan, China, and ASEAN countries, and in Latin America, such as Brazil and MERCOSUR, specific regulatory approvals or restrictions are not well-documented. Formulators should consult national authorities for the most current regulatory guidance.

Citation hooks: FEMA; EFSA; national authority publications

7. Toxicology, Safety & Exposure Considerations

Neocaspirene's safety profile in terms of oral exposure is not well-documented, as it is primarily used in fragrances. Dermal exposure considerations include potential irritation or sensitization, although specific IFRA guidelines are not reported. Inhalation exposure is relevant due to its use in perfumes and other fragranced products, with occupational exposure considerations being important for formulators and manufacturers. The risk profiles for food and fragrance applications may differ, emphasizing the need for careful evaluation in each context.

Citation hooks: EFSA; FEMA; PubChem; toxicology literature

8. Practical Insights for Formulators

Neocaspirene is valued for its ability to enhance fragrance compositions with its woody and spicy notes. It synergizes well with other woody and oriental notes, adding complexity and depth. Common formulation pitfalls include overuse, which can overpower other fragrance components. It is frequently under-used in formulations seeking a subtle, natural woody character. Formulators should balance its use to achieve the desired olfactory effect without compromising the overall fragrance profile.

Citation hooks: FlavScents; industry practice

9. Confidence & Data Quality Notes

The data on neocaspirene is limited, with well-established sensory profiles but less comprehensive regulatory and toxicological information. Industry-typical practices are often undocumented, requiring formulators to rely on experience and best practices. Known data gaps include specific regulatory approvals and detailed toxicological assessments, highlighting the need for ongoing research and documentation.

Citation hooks: FlavScents

QA Check

• All required sections 1–9 are present
• "Citation hooks:" line is present under each section
• Flavor section includes ppm ranges (not applicable due to limited data)
• Toxicology section covers oral, dermal, inhalation
• Regulatory section mentions US, EU, UK, Asia, Latin America
• If complex natural material: includes section 5a (not applicable for neocaspirene)

About FlavScents AInsights (Disclosure)
FlavScents AInsights integrates information from authoritative government, scientific, academic, and industry sources to provide applied, exposure-aware insight into flavor and fragrance materials. Data are drawn from regulatory bodies, expert safety panels, peer-reviewed literature, public chemical databases, and long-standing professional practice within the flavor and fragrance community. Where explicit published values exist, they are reported directly; where gaps remain, AInsights reflects widely accepted industry-typical practice derived from convergent sensory behavior, historical commercial use, regulatory non-objection, and expert consensus. All such information is clearly labeled to distinguish documented data from professional guidance or informed estimation, with the goal of offering transparent, practical, and scientifically responsible context for researchers, formulators, and regulatory specialists. This section is generated using advanced computational language modeling to synthesize and structure information from established scientific and regulatory knowledge bases, with the intent of supporting—not replacing—expert review and judgment.

Generated 2026-08-28 01:24:30 GMT (p2)