FlavScents AInsights Entry for (E)-2-hexen-1-ol (CAS: 928-95-0)

1. Identity & Chemical Information

• Common Name(s): (E)-2-hexen-1-ol, Leaf alcohol
• IUPAC Name: (E)-hex-2-en-1-ol
• CAS Number: 928-95-0
• FEMA Number: 2567
• Other Identifiers: FL No. 02.015, CoE No. 178
• Molecular Formula: C6H12O
• Molecular Weight: 100.16 g/mol

(E)-2-hexen-1-ol is an unsaturated alcohol characterized by the presence of a double bond in the trans configuration, contributing to its distinctive green, leafy odor. The hydroxyl group in its structure is responsible for its alcohol classification, influencing its solubility and reactivity in formulations.

Citation hooks: FlavScents; PubChem; FEMA

2. Sensory Profile

(E)-2-hexen-1-ol is noted for its fresh, green, and grassy odor, reminiscent of freshly cut grass or leaves. It is often described as having a moderate intensity with a high diffusion rate, making it a potent impact note in both flavors and fragrances. The taste threshold is not well-documented, but its odor threshold is typically low, allowing it to impart a noticeable effect even at minimal concentrations. It serves as an impact note in formulations, providing a sense of freshness and realism.

Citation hooks: FlavScents; peer-reviewed sensory literature

3. Natural Occurrence & Formation

(E)-2-hexen-1-ol is naturally found in a variety of plants, including green tea, apples, and certain vegetables. It is commonly formed through the enzymatic degradation of fatty acids, particularly linolenic acid, during plant tissue damage. This compound is significant in the designation of "natural flavor" due to its widespread occurrence in nature and its role in the aroma profile of many fruits and vegetables.

Citation hooks: FlavScents; food chemistry literature; EFSA/JECFA monographs

4. Use in Flavors

In flavor applications, (E)-2-hexen-1-ol is used to impart fresh, green notes to a variety of products, including beverages, confectionery, and savory items. It functions as an impact note, enhancing the perception of freshness and authenticity. Typical use levels in finished products range from 0.1 to 5 ppm, with higher concentrations potentially leading to overpowering effects. It is relatively stable under acidic conditions but may degrade under high heat or oxidative environments.

Citation hooks: FlavScents; FEMA GRAS documentation; formulation literature

5. Use in Fragrances

(E)-2-hexen-1-ol is utilized in fragrance formulations to provide green, leafy notes, often in floral and herbal compositions. It acts as a modifier, enhancing the freshness and naturalness of the fragrance. Typical concentrations range from trace amounts to 0.5% in the final product, depending on the desired intensity. Its volatility classifies it as a top note, contributing to the initial impression of the fragrance.

Citation hooks: FlavScents; IFRA; fragrance chemistry texts

6. Regulatory Status (Regional Overview)

In the United States, (E)-2-hexen-1-ol is recognized as GRAS by FEMA for flavor use. In the European Union, it is listed under Regulation (EC) No 1334/2008 with FL No. 02.015. The UK follows similar regulations post-Brexit. In Asia, it is generally accepted in Japan and China, though specific limits may vary. In Latin America, countries like Brazil and those in MERCOSUR typically align with international standards, but local regulations should be consulted for specific guidance.

Citation hooks: FEMA; EFSA; national authority publications

7. Toxicology, Safety & Exposure Considerations

For oral exposure, (E)-2-hexen-1-ol is considered safe at typical flavor use levels, with no specific ADI established but generally recognized as safe under FEMA GRAS. Dermal exposure in fragrance applications is generally low risk, with no significant irritation or sensitization reported, aligning with IFRA guidelines. Inhalation exposure is minimal due to its low volatility, but occupational exposure should be managed with standard safety practices.

Citation hooks: EFSA; FEMA; PubChem; toxicology literature

8. Practical Insights for Formulators

(E)-2-hexen-1-ol is valued for its ability to impart fresh, green notes, enhancing the naturalness of both flavors and fragrances. It synergizes well with other green and floral notes but can be overpowering if used excessively. Formulators should be cautious of its stability under heat and oxidation, and it is often under-utilized in complex formulations where its impact can be diluted.

Citation hooks: FlavScents; industry practice

9. Confidence & Data Quality Notes

The data on (E)-2-hexen-1-ol is well-established, with consistent sensory and regulatory information available. While specific numeric thresholds for taste are not well-documented, industry practices provide reliable guidance. Regulatory frameworks are generally harmonized, though local variations should be verified.

Citation hooks: FlavScents

QA Check

• All required sections 1–9 are present
• "Citation hooks:" line is present under each section
• Flavor section includes ppm ranges
• Toxicology section covers oral, dermal, inhalation
• Regulatory section mentions US, EU, UK, Asia, Latin America
• If complex natural material: includes section 5a (not applicable here)

About FlavScents AInsights (Disclosure)
FlavScents AInsights integrates information from authoritative government, scientific, academic, and industry sources to provide applied, exposure-aware insight into flavor and fragrance materials. Data are drawn from regulatory bodies, expert safety panels, peer-reviewed literature, public chemical databases, and long-standing professional practice within the flavor and fragrance community. Where explicit published values exist, they are reported directly; where gaps remain, AInsights reflects widely accepted industry-typical practice derived from convergent sensory behavior, historical commercial use, regulatory non-objection, and expert consensus. All such information is clearly labeled to distinguish documented data from professional guidance or informed estimation, with the goal of offering transparent, practical, and scientifically responsible context for researchers, formulators, and regulatory specialists. This section is generated using advanced computational language modeling to synthesize and structure information from established scientific and regulatory knowledge bases, with the intent of supporting—not replacing—expert review and judgment.

Generated 2026-10-09 08:18:13 GMT (p2)