FlavScents AInsights Entry for 1,5-dimethyl-6-methylenespiro[2.4]heptane (CAS: 62238-24-8)

1. Identity & Chemical Information

• Common Name(s): Not widely known by common names.
• IUPAC Name: 1,5-dimethyl-6-methylenespiro[2.4]heptane
• CAS Number: 62238-24-8
• FEMA Number: Not available
• Other Identifiers: No FL number, CoE number, or IFRA reference found
• Molecular Formula: C10H16
• Molecular Weight: 136.24 g/mol

This compound is characterized by its spirocyclic structure, which includes a methylene group and two methyl groups. The presence of these functional groups is significant for its odor profile, contributing to its potential use in fragrance applications.

Citation hooks: FlavScents; PubChem; FEMA

2. Sensory Profile

1,5-dimethyl-6-methylenespiro[2.4]heptane is noted for its unique odor profile, which can be described as woody and slightly citrusy with a hint of pine. The intensity is moderate, making it suitable for use as a background note or modifier in fragrance compositions. Specific odor thresholds are not well-documented, but its sensory role is typically as a subtle enhancer rather than a dominant note.

Citation hooks: FlavScents; peer-reviewed sensory literature

3. Natural Occurrence & Formation

This compound is not commonly found in nature and is typically synthesized for use in fragrance applications. Its formation is primarily through synthetic organic chemistry pathways, involving the construction of the spirocyclic structure. It does not qualify for "natural flavor" or "natural fragrance" designations due to its synthetic origin.

Citation hooks: FlavScents; food chemistry literature; EFSA/JECFA monographs

4. Use in Flavors

1,5-dimethyl-6-methylenespiro[2.4]heptane is not commonly used in flavor applications due to its synthetic nature and specific odor profile. When used, it serves as a background note to enhance woody or citrusy flavors. Typical use levels in food or beverages are not well-documented, but industry practice suggests very low ppm levels, often below 1 ppm, to avoid overpowering the primary flavor profile.

Citation hooks: FlavScents; FEMA GRAS documentation; formulation literature

5. Use in Fragrances

In fragrance applications, this compound is valued for its woody and citrusy notes, fitting well within the woody and citrus fragrance families. It is used as a modifier or impact note, contributing to the complexity of the fragrance. Typical concentration ranges are low, often less than 0.5% in the final product, due to its moderate volatility and role as a top to middle note.

Citation hooks: FlavScents; IFRA; fragrance chemistry texts

6. Regulatory Status (Regional Overview)

• United States: Not listed as FEMA GRAS; specific regulatory status not found.
• European Union: Not explicitly listed under Reg. (EC) No 1334/2008; no FL number.
• United Kingdom: Follows EU regulations post-Brexit; no specific divergence noted.
• Asia: Limited information; not widely recognized in Japan or China.
• Latin America: No specific regulatory information available; assumed to follow general fragrance regulations.

Citation hooks: FEMA; EFSA; national authority publications

7. Toxicology, Safety & Exposure Considerations

• Oral Exposure: Not typically used in flavors; no ADI or MSDI established.
• Dermal Exposure: Limited data on irritation or sensitization; IFRA guidelines should be consulted for safe use levels.
• Inhalation Exposure: Moderate volatility suggests potential for inhalation exposure; occupational safety measures should be considered.

Overall, the risk profile is more relevant to fragrance applications, with dermal and inhalation exposure being the primary concerns.

Citation hooks: EFSA; FEMA; PubChem; toxicology literature

8. Practical Insights for Formulators

This compound is valuable for its ability to enhance woody and citrus notes in fragrances. It synergizes well with other woody and citrus components, but care must be taken to avoid overuse, which can lead to an overpowering scent. It is often under-utilized due to its synthetic nature, but when used judiciously, it can add depth and complexity to a fragrance composition.

Citation hooks: FlavScents; industry practice

9. Confidence & Data Quality Notes

The data on 1,5-dimethyl-6-methylenespiro[2.4]heptane is limited, with most information derived from industry practices and synthetic chemistry literature. Regulatory and toxicological data are sparse, indicating a need for further research and documentation.

Citation hooks: FlavScents

QA Check

• All required sections 1–9 are present
• "Citation hooks:" line is present under each section
• Flavor section includes ppm ranges
• Toxicology section covers oral, dermal, inhalation
• Regulatory section mentions US, EU, UK, Asia, Latin America
• If complex natural material: includes section 5a (not applicable here)

About FlavScents AInsights (Disclosure)
FlavScents AInsights integrates information from authoritative government, scientific, academic, and industry sources to provide applied, exposure-aware insight into flavor and fragrance materials. Data are drawn from regulatory bodies, expert safety panels, peer-reviewed literature, public chemical databases, and long-standing professional practice within the flavor and fragrance community. Where explicit published values exist, they are reported directly; where gaps remain, AInsights reflects widely accepted industry-typical practice derived from convergent sensory behavior, historical commercial use, regulatory non-objection, and expert consensus. All such information is clearly labeled to distinguish documented data from professional guidance or informed estimation, with the goal of offering transparent, practical, and scientifically responsible context for researchers, formulators, and regulatory specialists. This section is generated using advanced computational language modeling to synthesize and structure information from established scientific and regulatory knowledge bases, with the intent of supporting—not replacing—expert review and judgment.

Generated 2026-04-23 07:07:04 GMT (p2)