FlavScents AInsights Entry for Caprylic/Capric Triglyceride (CAS: 65381-09-1)

1. Identity & Chemical Information

Caprylic/capric triglyceride, commonly known as medium-chain triglycerides (MCT), is a mixture of triglycerides derived from caprylic (C8) and capric (C10) fatty acids. It is not a single compound but a blend, typically sourced from coconut or palm kernel oil. The CAS number for this material is 65381-09-1. It does not have a specific FEMA number due to its complex nature. The molecular formula is not applicable as it is a mixture, but the average molecular weight is approximately 512 g/mol. The functional groups present are ester linkages, which contribute to its stability and non-volatile nature, making it odorless and tasteless.

Citation hooks: FlavScents; PubChem; FEMA

2. Sensory Profile

Caprylic/capric triglyceride is characterized by its lack of odor and flavor, making it an ideal carrier oil in both flavor and fragrance applications. Its sensory role is primarily as a diluent or carrier, providing a neutral base that does not interfere with the sensory characteristics of other ingredients. Due to its non-volatile nature, it does not contribute to the aroma profile of formulations.

Citation hooks: FlavScents; peer-reviewed sensory literature

3. Natural Occurrence & Formation

Caprylic/capric triglyceride is naturally derived from coconut oil and palm kernel oil. It is formed through the esterification of glycerol with medium-chain fatty acids, primarily caprylic and capric acids. This material is often used in products labeled as "natural" due to its derivation from natural sources, although the processing involved may affect its designation in certain regulatory contexts.

Citation hooks: FlavScents; food chemistry literature; EFSA/JECFA monographs

4. Use in Flavors

In flavor applications, caprylic/capric triglyceride serves as a carrier or solvent for flavor compounds, particularly in oil-based systems. It is used across various flavor categories, including beverages, dairy, and confections. Typical use levels range from 100 to 1000 ppm, depending on the specific application and desired flavor intensity. It is valued for its stability under heat and neutral pH conditions, which helps preserve the integrity of flavor compounds.

Citation hooks: FlavScents; FEMA GRAS documentation; formulation literature

5. Use in Fragrances

Caprylic/capric triglyceride is widely used in fragrance formulations as a carrier oil. It is compatible with a variety of fragrance families and product types, including perfumes, lotions, and creams. Its role is primarily as a diluent, providing a stable, non-reactive base that enhances the longevity and diffusion of fragrance compounds. Typical concentration ranges are qualitative, as it is often used in substantial proportions relative to the active fragrance ingredients.

Citation hooks: FlavScents; IFRA; fragrance chemistry texts

6. Regulatory Status (Regional Overview)

In the United States, caprylic/capric triglyceride is generally recognized as safe (GRAS) for use in food products. The European Union permits its use under Regulation (EC) No 1334/2008, and it is assigned an FL number for flavoring purposes. In the United Kingdom, post-Brexit regulations align closely with EU standards. In Asia, including Japan and China, it is approved for use in food and cosmetics, with specific guidelines varying by country. In Latin America, it is accepted under MERCOSUR regulations, with Brazil having specific labeling requirements.

Citation hooks: FEMA; EFSA; national authority publications

7. Toxicology, Safety & Exposure Considerations

Caprylic/capric triglyceride is considered safe for oral exposure, with an acceptable daily intake (ADI) not specifically established due to its GRAS status. Dermal exposure is also deemed safe, with low potential for irritation or sensitization, making it suitable for use in cosmetics and personal care products. Inhalation exposure is minimal due to its low volatility. The risk profiles for food and fragrance applications are similar, with no significant safety concerns reported.

Citation hooks: EFSA; FEMA; PubChem; toxicology literature

8. Practical Insights for Formulators

Caprylic/capric triglyceride is valued for its versatility and stability, making it a staple in both flavor and fragrance formulations. It synergizes well with a wide range of compounds, enhancing solubility and stability. Common pitfalls include overuse, which can lead to a greasy texture in food applications or an overly oily feel in cosmetics. It is often under-utilized in formulations requiring a neutral carrier.

Citation hooks: FlavScents; industry practice

9. Confidence & Data Quality Notes

The data on caprylic/capric triglyceride is well-established, with extensive documentation supporting its safety and efficacy. Industry practices are consistent, though specific use levels may vary based on formulation needs. There are no significant data gaps, but ongoing research into its broader applications continues to refine its use.

Citation hooks: FlavScents

QA Check

• All required sections 1-9 are present
• "Citation hooks:" line is present under each section
• Flavor section includes ppm ranges
• Toxicology section covers oral, dermal, inhalation
• Regulatory section mentions US, EU, UK, Asia, Latin America
• If complex natural material: includes section 5a (not applicable here)

About FlavScents AInsights (Disclosure)
FlavScents AInsights integrates information from authoritative government, scientific, academic, and industry sources to provide applied, exposure-aware insight into flavor and fragrance materials. Data are drawn from regulatory bodies, expert safety panels, peer-reviewed literature, public chemical databases, and long-standing professional practice within the flavor and fragrance community. Where explicit published values exist, they are reported directly; where gaps remain, AInsights reflects widely accepted industry-typical practice derived from convergent sensory behavior, historical commercial use, regulatory non-objection, and expert consensus. All such information is clearly labeled to distinguish documented data from professional guidance or informed estimation, with the goal of offering transparent, practical, and scientifically responsible context for researchers, formulators, and regulatory specialists. This section is generated using advanced computational language modeling to synthesize and structure information from established scientific and regulatory knowledge bases, with the intent of supporting—not replacing—expert review and judgment.

Generated 2026-09-08 21:03:07 GMT (p2)